Can i take 3000 mg of lysine at once

While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by the medical community, and whether studies have found them to be effective for other people.

For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings.

We hope this provides you with a helpful resource to make informed decisions towards your health and well-being. For a supplement, little scientific support. The amino acid lysine has been reported to reduce the recurrence rate of herpes simplex infections in both preliminary and double-blind trials. The amount used in these studies was usually 1 to 3 grams per day, although some people received as little as mg per day.

In one double-blind trial, lysine supplementation 1, mg per day failed to prevent recurrences better than placebo. However, the results of that study may have been skewed by a large number of dropouts in the placebo group who fared poorly but were not included in the analysis. When lysine has been used for acute outbreaks, the results have been mixed. In a preliminary study, mg of lysine taken at the first sign of a herpes outbreak resulted in rapid resolution of the cold sores in all cases.

However, in a double-blind study, supplementing with 1 gram of lysine per day for five days did not increase the healing rate of the cold sores. Most research on lysine has been done on people with cold sores or on groups that include both cold sores and genital herpes sufferers. However, some evidence exists that supplemental lysine may be effective in the prevention and treatment of genital herpes.

A small double-blind trial of people with oral and genital herpes examined the effects of 1, mg or mg of lysine daily versus placebo. Another small double-blind trial found that using 3, mg per day of lysine in divided doses led to a decrease in severity of symptoms and a reduction in healing time of both oral and genital herpes. One preliminary report found no benefit of lysine for a group of patients with either oral or genital herpes.

Because shingles is caused by a herpes virus, some doctors believe that lysine supplementation could help people with the condition, since lysine inhibits replication of herpes simplex, a related virus.

However, lysine has not been shown to inhibit Varicella zoster, nor has it been shown to provide any benefit for people with shingles outbreaks. Therefore, its use in this condition remains speculative. Most people do not require lysine supplementation.

Doctors often suggest that people with recurrent herpes simplex infections take 1,—3, mg of lysine per day. Brewer's yeast , legumes, dairy, fish, and meat all contain significant amounts of lysine.

Most people, including vegans vegetarians who also avoid dairy and eggs , consume adequate amounts of lysine. However, vegans whose diets contain large amounts of grains and only minimal amounts of beans could become deficient in lysine.

The virus then migrates to the skin and mucosa cells causing injuries and recurrent infections which are called secondary or recurrent herpetic gingivostomatitis or only herpes labialis. The simple herpes labialis, in immunocompetent patients, evolves through 3 clinical periods of the disease.

The first 24 hours before the disease manifestation is called latent or prodromal period figure 1A. The active clinical period is related to the appearance of the first papules remaining 2 to 4 days figure 1B. At the end of the cycle - reparatory period - the vesicles are reduced and remain, on average from 2 to 4 days figure 2A , until final total repair figure 2B [ 4 4 Consolaro A, Consolaro MF.

Figure 1 A Injury in 12 hours - prodromal period; B Injury in 72 hours -active clinical period. The supplementation of L-lysine is safe. Doses of up to 3g per day are well tolerated; however, higher doses g per day can cause gastrointestinal disturbances, including nausea, abdominal cramps and diarrhea. Rio de Janeiro: Guanabara Koogan; Lysine kinetics at graded lysine intakes in young men. Am J Clin Nutr. Lysine requirement of adult males is not affected by decreasing dietary protein.

Prophylaxis against herpes simplex virus reactivation in patients with facial burns: a-potential role for l-lysine. J Burn Care Res. Effect of L-Lysine-a-oxidase on reproduction of herpes simplex type 1 virus in vitro. Vopr Med Khim. Antiherpetic Activity of L-Lysine-alpha-oxidase in different dosage forms. Antibiot Khimioter. Success of L-lysine therapy in frequently recurrent Herpes simplex infection.

Treatment and prophylaxis. Use of lysine in treating recurrent oral Herpes simplex infections. Gen Dent. A multicentered study of lysine therapy in Herpes simplex infection.

Lysine prophylaxis in recurrent Herpes simplex labialis: a double-blind, controlled crossover study. Acta Derm Venereol. Relation of arginine-lysine antagonism to Herpes simplex growth in tissue culture.

Lysine as a prophylactic agent in the treatment of recurrent herpes simplex labialis. The objective of this study was to show, through clinical observation, a significant effect on the annual incidence reduction of recurrent herpes in a 8-year follow up. The prospective study was conducted in a group of 12 individuals, being five males and seven females aged between 30 and 48 years old, suffering from recurrent herpes labialis lesions with manifestations ranging from over one or more episode per month to one or more every three months.

All members belonged to the same socio-economic and cultural class and they had never received any systemic therapy prior to the study. Regarding the topical treatment, antiviral acyclovir cream were used three times a day since the first signal of the lesion. Also Read: How to prevent Cold Sores 9 ways. Lysine is an amino acid, also known as a building block of proteins.

Taking Lysine by mouth may have benefits in reducing the recurrences of cold sores and lessening the severity and healing time of cold sores. There may even be benefits of increased healing speed by applying Lysine based medications topically in ointment form. The mechanism behind how Lysine helps with cold sores is thought to be due to its ability to block Arginine , which the herpes virus uses to replicate.

Lysine may also help support the immune system to better combat viral infections. One older questionnaire study enrolled participants with either herpes labialis cold sores or genital herpes and had some of them take Lysine supplements. A placebo-controlled study had 27 patients with herpes take 1,mg Lysine 3 times daily for 6 months, and had 25 herpes patients take a placebo 3 times daily.

At the end of the 6 months, the group taking Lysine had an average of 2. However, some studies, like this study by DiGiovanna , did not find any benefits of Lysine supplementation compared to placebo.

But, this could be due to the dosing being much lower than some of the other studies at only mg three times daily. According to the Natural Medicines supplement database, they recommend the following dosages for cold sore prevention and treatment:. Lysine is normally well tolerated at recommended dosages, but higher dosages may have more risks of the following side effects. The most common side effects of Lysine supplementation are diarrhea, cramps, abdominal pain, and nausea.

If you are prone to kidney or gallstone issues, consult with your doctor before starting Lysine supplementation. There are no reported interactions between taking Lysine with a prescription cold sore treatment like Valacyclovir. If your cold sore breakouts are frequent and intense, you may benefit from speaking with a doctor about prescription anti-viral medications like Valacyclovir generic Valtrex. You can have an Online Visit with our doctors today to see if Valacyclovir treatment is a good option for your cold sore breakouts - maybe along with some additional Lysine.

Select a treatment to get started For him. Hair loss.